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KMID : 1013220060040010061
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Jouranl of the Korean Society of Clinical Toxicology
2006 Volume.4 No. 1 p.61 ~ p.64
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A Case of anterograde amnesia with hippocampal lesions following glufosinate intoxication
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Seol Seung-Hwan
Park Hyeon-Soo
Ahn Jung-Hwan
Kim Gi-Woon
Park Hee-Young
Lee Phil-Hyu
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Abstract
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Glufosinate ammonium (GLA), a phosphinic acid derivate of glutamate, is a broad-spectrum contact herbicide. It structurally resembles glutamate, a typical excitatory amino acid in the central nervous system. In korea, the ingestion of GLA for suicidal attempt or accidental event has increased. The neurological complication of GLA intoxication are characterized by loss of consciousness, convulsion, or memory impairment. But, the exact mechanism of GLA toxicity is yet unknown. This report is about a patient with GLA intoxication who showed anterograde amnesia with selective bilateral hip-pocampal lesions supported GLA intoxication with literature reviews supported.
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KEYWORD
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Glufosinate ammonium, Intoxication, Anterograde ammesia
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